CQ-16 - CAS 3024354-59-1

CQ-16 is an orally active small molecule drug conjugate (SMDC) that targets prostate-specific membrane antigen (PSMA) . It exhibits high selectivity in its antiproliferative activity between PSMA-positive and PSMA-negative prostate cells. Additionally, CQ-16 possesses PARP inhibitory activity (IC50=1 nM) .

PSMA, Epigenetic Reader Domain, PARP, PROTACs

Chromatin/Epigenetic, Immunology/Inflammation, DNA Damage/DNA Repair, PROTAC

3024294

C40H47FN8O12

850.85

C(=O)(C1(NC(CCC(NCCCC[C@H](NC(N[C@@H](CCC(O)=O)C(O)=O)=O)C(O)=O)=O)=O)CC1)N2CCN(C(=O)C3=CC(CC=4C=5C(C(=O)NN4)=CC=CC5)=CC=C3F)CC2

-20°C

Ice Packs

PROTAC