CRA-026440 - CAS 847460-34-8

CRA-026440 (PCI-34051) is a highly potent HDAC inhibitor with inhibitory effects on HDAC1, HDAC2, HDAC3, HDAC6, HDAC8 and HDAC10 with Ki values of 4,14,11,15,7 and 20 nM, respectively. CRA-026440 has anti-tumor and anti-angiogenic activity and can be used to study colon cancer.

Apoptosis, HDAC

Chromatin/Epigenetic, DNA Damage/DNA Repair, Apoptosis

847418

0.9642

C23H24N4O4

420.46

O=C(NO)C1=CC=C(C#CCNC(=O)C2=CC=3C=C(OCCN(C)C)C=CC3N2)C=C1

-20°C

Ice Packs

Small Compound