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Crelosidenib - CAS 2230263-60-0

Crelosidenib - CAS 2230263-60-0

MF-0000177-01

$398.37 USD
$258.05 USD $398.37 USD
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Product Details

  • Bioactivity

    Crelosidenib is a potent and selective mutant IDH inhibitor with IC50s of 6.27 nM, 3.71 nM, 36.9 nM, and 11.5 nM for IDH1 R132H, IDH1 R132C, IDH2 R140Q, and IDH2 R172K mutases, respectively, and low inhibitory activity against the wild-type IDH enzyme.

  • Target

    Isocitrate Dehydrogenase (IDH), Dehydrogenase

  • Related Pathways

    Metabolism

  • CAS Number

    2230263-60-0

  • Purity

    0.9854

  • Molecular Formula

    C28H36N6O3

  • Molecular Weight

    504.62

  • SMILES

    [C@H](CC1CC1)(C2=CC=C([C@@H](NC=3N=C4C(=CN3)COC(=O)N4CC)C)C=C2)N5CCN(C(C=C)=O)CC5

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound