CRIPGBM - CAS 2361988-76-1

CRIPGBM, a proapoptotic derivative of RIPGBM, selectively induces apoptosis in GBM cancer stem cells (CSCs) by targeting receptor-interacting protein kinase 2 (RIPK2), demonstrating an EC50 of 68 nM in GBM-1 cells [1].

Apoptosis, RIP kinase, TNF

Apoptosis, NF-κB

2361911

C26H20FN2O2

411.45

C([N+]=1C2=C(N(CC3=CC=CC=C3)C1C)C(=O)C=4C(C2=O)=CC=CC4)C5=CC=C(F)C=C5

-20°C

Ice Packs

Small Compound