Crizotinib - CAS 877399-52-5

Crizotinib (PF-02341066) is an ATP-competitive small-molecule tyrosine kinase inhibitor of c-MET (IC50: 8 nM) and ALK (IC50: 20 nM) receptors.

C-Met/HGFR, Autophagy, ROS Kinase, ALK, ROS

Autophagy, Angiogenesis, Immunology/Inflammation, Tyrosine Kinase/Adaptors

877342

0.9987

C21H22Cl2FN5O

450.34

O([C@H](C)C1=C(Cl)C(F)=CC=C1Cl)C2=CC(C3=CN(N=C3)C4CCNCC4)=CN=C2N

-20°C

Ice Packs

Small Compound