Crizotinib-d5 - CAS 1395950-84-1

Crizotinib-d5 is a deuterated compound of Crizotinib. Crizotinib has a CAS number of 877399-52-5. Crizotinib is an ATP-competitive small-molecule tyrosine kinases inhibitor of c-MET (IC50: 8 nM) and ALK (IC50: 20 nM) receptor.

ROS Kinase, Autophagy, c-Met/HGFR, ALK

Angiogenesis, Tyrosine Kinase/Adaptors, Autophagy

1395950-84-1

C21H17D5Cl2FN5O

455.37

C1(F)C(Cl)=C([C@H](OC2C=C(C3C=NN(C4([2H])C([2H])([2H])CNCC4([2H])[2H])C=3)C=NC=2N)C)C(Cl)=CC=1

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