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Crizotinib hydrochloride - CAS 1415560-69-8

Crizotinib hydrochloride - CAS 1415560-69-8

SKU:MF-0016234-01

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  • Bioactivity

    Crizotinib hydrochloride (PF-02341066 hydrochloride) is a novel inhibitor of anaplastic lymphoma kinase and c-Met, with IC50 values of 20 nM and 8 nM, respectively.

  • Target

    ROS Kinase, Autophagy, c-Met/HGFR, ROS, ALK

  • Related Pathways

    Angiogenesis, Autophagy, Immunology/Inflammation, Tyrosine Kinase/Adaptors

  • CAS Number

    1415483

  • Purity

    0.9967

  • Molecular Formula

    C21H23Cl3FN5O

  • Molecular Weight

    486.8

  • SMILES

    Cl.C[C@@H](Oc1cc(cnc1N)-c1cnn(c1)C1CCNCC1)c1c(Cl)ccc(F)c1Cl

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound