CRSP-1 - CAS 697327-12-1

Endogenous central calcitonin (CT) receptor agonist that stimulates cAMP formation at a potency 350-fold greater than CT (ED50 values are 0.2 and 71 nM respectively) . Displays no activity at calcitonin-gene related peptide (CGRP) and adrenomedullin receptors. Inhibits formation of multinuclear osteoclasts with similar efficacy to CT in vitro. Suppresses food intake and increases body temperature in free-feeding rats, and significantly decreases plasma calcium levels in vivo.

CGRP Receptor

Neuroscience, GPCR/G Protein

697314

C175H294N54O49S5

4098.88

-20°C

Ice Packs

Peptide