CRT0066101 - CAS 956123-34-5

CRT0066101 is a potent, orally active PKD inhibitor with IC 50 values of 1 nM, 2.5 nM, and 2 nM for PKD1, PKD2, and PKD3, respectively [1]. Additionally, it inhibits PIM2 with an IC 50 of approximately 135.7 nM and demonstrates anticancer effects [2].

Apoptosis, Pim, Serine/threonin kinase

Apoptosis, Chromatin/Epigenetic, Cell Cycle/Checkpoint, JAK/STAT signaling, Metabolism

956123-34-5

C18H22N6O

338.41

OC=1C(=CC(=CC1)C2=CN(C)N=C2)C=3N=C(NC[C@@H](CC)N)C=CN3

-20°C

Ice Packs

Small Compound