Cryogenine - CAS 10308-13-1

Cryogenine is an alkaloid originally isolated from H. salicifolia that exhibits anti-inflammatory activity. It inhibits prostaglandin synthetase (IC50 = 424 μM) and, at a dosage of 100 mg/kg per day (p.o.), reduces paw edema and the mean arthritic index in a rat model of adjuvant-induced polyarthritis.

Others, PGE Synthase

Others, Immunology/Inflammation

10294

C26H29NO5

435.52

[H][C@]12C[C@@]3([H])CCCCN3[C@@]([H])(C1)c1cc(OC)c(OC)cc1-c1cc(ccc1O)\C=C/C(=O)O2 |c:34|

-20°C

Ice Packs

Small Compound