CS-526 - CAS 313272-12-7

CS-526 is a proton pump inhibitor. The inhibitory mechanism of CS-526 on H+, K+-ATPase was a competitive antagonism to the K+ binding site of H+, K+-ATPase, and it was also a reversible inhibition. CS-526 has a potent antisecretory effect on gastric acid secretion without rebound gastric hypersecretion. CS-526 inhibited acute gastric mucosal lesions. CS-526 inhibited histamine-stimulated gastric acid secretion in a dose- and retention time-dependent manner.

Proton pump, Others

Membrane transporter/Ion channel, Others

313253

C20H22FN3O

339.41

C(N1C=2C(C(C)=C1C)=CN=NC2OCC3=CC=C(F)C=C3)[C@@H]4[C@@H](C)C4

-20°C

Ice Packs

Small Compound