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Molfinity

CSN5i-3 - CAS 2375740-98-8

CSN5i-3 - CAS 2375740-98-8

MF-0017441-01

$381.69 USD
$381.69 USD
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Product Details

  • Bioactivity

    CSN5i-3 is a potent, selective, and orally available inhibitor of the proteolytic subunit of the CSN complex, CSN5. It inhibits CSN-catalyzed Cul1 deneddylation with an IC50 value of 5.8 nM. CSN5i-3 has a killing effect on a variety of cancer cells and can be used as an anticancer drug. [2]

  • Target

    Apoptosis, Others

  • Related Pathways

    Others, Apoptosis

  • CAS Number

    2375634

  • Purity

    >99.99%

  • Molecular Formula

    C28H29F2N5O2

  • Molecular Weight

    505.56

  • SMILES

    CC(C)n1nc(cc1C(=O)Nc1ccc([C@H]2[C@@H](O)CCCc3cncn23)c(c1)-c1ccccc1)C(F)F

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound