CST 530 - CAS 847137-53-5

CST 530 is a monovalent IAP antagonist. It induces cIAP1 and cIAP2 autodegradation in MM.1S cells (cIAP1 degradation at 0.1 μM and cIAP2 degradation at 1 μM after 16 hours) . CST 530 reduces cell viability in multiple cancer cell lines including SUDHL6, MOLM13, and HEL (IC50 values ​​of 170 nM, 420 nM, and 450 nM, respectively) .

Ligand for E3 Ligase, Apoptosis, IAP

PROTAC, Apoptosis

847079

C33H44N4O4

560.727

C([C@@H](NC([C@@H](NC)C)=O)C1CCCCC1)(=O)N2[C@H](C(N[C@H]3C=4C(CCC3)=CC=CC4)=O)C[C@H](OC5=CC=CC=C5)C2

-20°C

Ice Packs

Small Compound