CTPI-2 - CAS 68003-38-3

CTPI-2 is an inhibitor of mitochondrial citrate carrier SLC25A1 with (KD : 3.5 μM) . CTPI-2 inhibits glycolysis, PPARγ, and its downstream target the glucose transporter GLUT4. CTPI-2 exhibits anti-tumor activity.CTPI-2 halts salient alterations of NASH reverting steatosis, preventing the evolution to steatohepatitis, reducing inflammatory macrophage infiltration in the liver and adipose tissue, and starkly mitigating obesity induced by a high-fat diet.

Mitochondrial Metabolism

Metabolism

67962

0.9791

C13H9ClN2O6S

356.74

OC(=O)c1ccccc1NS(=O)(=O)c1ccc(Cl)c(c1)[N+]([O-])=O

-20°C

Ice Packs

Small Compound