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Cucurbitacin IIA - CAS 58546-34-2
Cucurbitacin IIA - CAS 58546-34-2
SKU:MF-0096738-01
Regular price
$32.42 USD
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$32.42 USD
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Product Details
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Bioactivity
1. Cucurbitacin IIA (Dihydrocucurbitacin Q1) can induce apoptosis and enhance autophagy , contributes to the anti-inflammatory activity of Cucurbitacin IIA against inflammation-related diseases. 2. Cucurbitacin IIA is a novel class of anti-cancer drug in suppression of cancer cell expansion by disrupting the actin cytoskeleton and directing the cell to undergo PARP-mediated apoptosis through the inhibition of survivin downstream of JAK2/STAT3.
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Target
Survivin, Apoptosis
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Related Pathways
Apoptosis
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CAS Number
58510
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Purity
0.9987
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Molecular Formula
C32H50O8
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Molecular Weight
562.73
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SMILES
[H][C@@]1([C@H](O)C[C@@]2(C)[C@]3([H])CC=C4[C@@]([H])(C[C@H](O)[C@@H](O)C4(C)C)[C@]3(C)C(=O)C[C@]12C)[C@@](C)(O)C(=O)CCC(C)(C)OC(C)=O
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Natural Product