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Cucurbitacin IIA - CAS 58546-34-2

Cucurbitacin IIA - CAS 58546-34-2

SKU:MF-0096738-01

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  • Bioactivity

    1. Cucurbitacin IIA (Dihydrocucurbitacin Q1) can induce apoptosis and enhance autophagy , contributes to the anti-inflammatory activity of Cucurbitacin IIA against inflammation-related diseases. 2. Cucurbitacin IIA is a novel class of anti-cancer drug in suppression of cancer cell expansion by disrupting the actin cytoskeleton and directing the cell to undergo PARP-mediated apoptosis through the inhibition of survivin downstream of JAK2/STAT3.

  • Target

    Survivin, Apoptosis

  • Related Pathways

    Apoptosis

  • CAS Number

    58510

  • Purity

    0.9987

  • Molecular Formula

    C32H50O8

  • Molecular Weight

    562.73

  • SMILES

    [H][C@@]1([C@H](O)C[C@@]2(C)[C@]3([H])CC=C4[C@@]([H])(C[C@H](O)[C@@H](O)C4(C)C)[C@]3(C)C(=O)C[C@]12C)[C@@](C)(O)C(=O)CCC(C)(C)OC(C)=O

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Natural Product