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Cutamesine dihydrochloride - CAS 165377-44-6

Cutamesine dihydrochloride - CAS 165377-44-6

SKU:MF-0094585-01

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  • Bioactivity

    Cutamesine dihydrochloride (SA4503 dihydrochloride) is a selective σ1 receptor agonist (IC50: 17.4 nM) . It shows selectivity for σ1 over σ2 receptors, and inhibits angiotensin II-induced cardiomyocyte hypertrophy in vitro and attenuates myocardial hypertrophy in vivo. In a rat model of experimental stroke, it enhances brain plasticity and sensorimotor function.

  • Target

    Sigma receptor

  • Related Pathways

    GPCR/G Protein

  • CAS Number

    165327

  • Purity

    0.9996

  • Molecular Formula

    C23H32N2O2·2HCl

  • Molecular Weight

    441.43

  • SMILES

    Cl.Cl.COc1ccc(CCN2CCN(CCCc3ccccc3)CC2)cc1OC

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound