CVN293 - CAS 2815296-08-1

CVN293 is a selective inhibitor of the potassium channel KCNK13, with the advantages of brain permeability and oral bioavailability. It inhibits the production of the pro-inflammatory cytokine IL-1β induced by NLRP3 in microglia and can be used for research into neurodegenerative diseases.

NOD-like Receptor (NLR), NOD, Potassium Channel, IL Receptor

Immunology/Inflammation, NF-κB, Membrane transporter/Ion channel

2815296-08-1

0.995

C14H10FN7O

311.27

C(N1C(=NC=2C1=C(F)C=CC2)C=3C(N)=NON3)C4=CC=CN=N4

-20°C

Ice Packs

Small Compound