CWP232228 - CAS 1144044-02-9

CWP232228, a potent and selective Wnt / β-catenin signaling inhibitor, antagonizes the binding of β-catenin to T-cell factor (TCF) in the nucleus. CWP232228 inhibits the formation and metastasis of tumors by inhibiting the growth of breast cancer and liver cancer stem cells (CSC) without toxicity.

Wnt/beta-catenin

Cytoskeletal Signaling, Stem Cells

1144044-02-9

0.9887

C33H34N7Na2O7P

717.63

O=C(NCC1=CC=CC=C1)N(N(CC2=O)CC=C)[C@]([H])(N2[C@H](C3=O)CC4=CC=C(C=C4)OP([O-])([O-])=O)CN3CC5=CC=CC6=CN(N=C56)C.[Na+].[Na+]

-20°C

Ice Packs

Small Compound