CXCR2 antagonist 3 - CAS 2647464-92-2

CXCR2 antagonist 3 (compound 11h) is a highly effective inhibitor of CXC chemokine receptor 2 (CXCR2), displaying double-digit nanomolar potencies in inhibiting neutrophil infiltration into the air pouch. Additionally, it reduces neutrophil and MDSC infiltration while enhancing CD3+ T lymphocyte infiltration into Pan02 tumor tissues [1].

CXCR, Others

GPCR/G Protein, Others, Autophagy, Immunology/Inflammation

2647370

C17H15FN2O4S

362.38

OC1=C2C(=CC=C1NC(NC3=C(C)C(F)=CC=C3)=O)C=CCS2(=O)=O

-20°C

Ice Packs

Small Compound