CXCR2-IN-2 - CAS 1838123-21-9

CXCR2-IN-2 (compound 68) is a highly selective CXCR2 antagonist (IC50=5.2 nM) with the advantages of blood-brain barrier penetration and oral bioavailability. It inhibits Gro-α-induced CD11b expression in human whole blood (IC50=0.04 μM) .

CXCR

Autophagy, GPCR/G Protein, Immunology/Inflammation

1838093

C18H23ClN2O5S

414.9

S(=O)(=O)(C1=C(O)C(NC(N[C@H]2C(C)=CCC2)=O)=CC=C1Cl)[C@@]3(C)CCOC3

-20°C

Ice Packs

Small Compound