CXCR4 antagonist 8 - CAS 2304750-84-1

CXCR4 antagonist 8 (Compound 3) is a potent inhibitor of CXCR4, exhibiting an IC50 value of 57 nM in antagonism and effectively inhibiting CXCL12-induced cytosolic calcium increase with an IC50 of 0.24 nM. Additionally, Compound 3 is efficacious in inhibiting CXCL12/CXCR4-mediated cell migration [1].

Others, CXCR

GPCR/G Protein, Others, Autophagy, Immunology/Inflammation

2304665

C21H26N6

362.47

N(CC=1C=C(N=C(C)N1)N2CCN(C)CC2)(C)C=3C4=C(C=CC3)C=CC=N4

-20°C

Ice Packs

Small Compound