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Molfinity

Cyclopamine - CAS 4449-51-8

Cyclopamine - CAS 4449-51-8

SKU:MF-0094115-01

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  • Bioactivity

    Cyclopamine (11-Deoxojervine), a Smoothened (Smo) antagonist (IC50: 46 nM in TM3Hh12 cells), belongs to the group of steroidal jerveratrum alkaloids.

  • Target

    Endogenous Metabolite, Hedgehog/Smoothened, Smo

  • Related Pathways

    Metabolism, GPCR/G Protein, Stem Cells

  • CAS Number

    4390

  • Purity

    0.9966

  • Molecular Formula

    C27H41NO2

  • Molecular Weight

    411.62

  • SMILES

    [H][C@@]12CC3O[C@]4([H])C[C@H](C)CN[C@@]4([H])[C@@H](C)[C@@]3([H])C(C)=C1C[C@@]1([H])[C@@]2([H])CC=C2C[C@@H](O)CC[C@]12C

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Natural Product