Cyclorasin 9A5 - CAS 1782098-79-6

Cyclorasin 9A5 is a cell-permeable, 11-residue cyclic peptide that orthosterically disrupts the Ras-Raf protein interaction, demonstrating an inhibition concentration (IC50) of 120 nM [1].

Raf, Ras

GPCR/G Protein, MAPK

1782098-79-6

C75H108FN25O13

1586.82

C(C=1C=2C(NC1)=CC=CC2)[C@@H]3NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](CCCC)NC(=O)[C@H](CC4=CC=C(F)C=C4)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](CC5=CC6=C(C=C5)C=CC=C6)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)NC(=O)[C@]([C@@H](C)O)(NC3=O)[H]

-20°C

Ice Packs

Peptide