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Cyclosporin A - CAS 59865-13-3

Cyclosporin A - CAS 59865-13-3

SKU:MF-0003997-01

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  • Bioactivity

    Cyclosporin A is a natural product and an active fungal metabolite, classified as a cyclic polypeptide immunosuppressant. It binds to cyclophilin and inhibits the activity of calcineurin (IC50 = 7 nM) as well as CD11a/CD18 adhesion molecules. It is commonly used to induce uremia models.

  • Target

    Phosphatase, Complement System, Antibiotic

  • Related Pathways

    Microbiology/Virology, Metabolism, Immunology/Inflammation

  • CAS Number

    59849

  • Purity

    0.9999

  • Molecular Formula

    C62H111N11O12

  • Molecular Weight

    1202.61

  • SMILES

    [C@H]([C@@H](C/C=C/C)C)(O)[C@@]1(N(C)C(=O)[C@H]([C@@H](C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H]([C@H](C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C(=O)[C@H](CC)NC1=O)[H]

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Natural Product