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CYP4A11/CYP4F2-IN-2 - CAS 2280834-99-1
CYP4A11/CYP4F2-IN-2 - CAS 2280834-99-1
SKU:MF-0147427-01
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Product Details
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Bioactivity
CYP4A11/CYP4F2-IN-2 (compound 15) serves as an orally administered inhibitor targeting CYP4A11/4F2, exhibiting IC50 values of 120 nM and 220 nM, respectively. This compound effectively suppresses 20-HETE production within the rat kidney and shows promise in mitigating the progression of diabetic nephropathy and autosomal dominant polycystic kidney disease [1].
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Target
Cytochromes P450
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Related Pathways
Metabolism
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CAS Number
2280834-99-1
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Molecular Formula
C19H27N3O4
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Molecular Weight
361.44
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SMILES
O(CCCCCCCOC(C(O)=O)(C)C)C1=CC=C(N=C1)C=2C=CNN2
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound