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Molfinity

Cys-McMMAF - CAS 1160590-05-5

Cys-McMMAF - CAS 1160590-05-5

SKU:MF-0155024-01

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  • Bioactivity

    Cys-McMMAF, the active compound liberated from AlMcMMAF—a humanized anti-5T4 A1 antibody connected to the microtubule-disrupting molecule MMAF through a maleimidocaproyl linker—demonstrates antitumor effectiveness in two mouse tumor models (H1975 and MDA-MB-361-DYT2) [1].

  • Target

    Microtubule Associated, Others

  • Related Pathways

    Cytoskeletal Signaling, Others

  • CAS Number

    1160590-05-5

  • Molecular Formula

    C52H83N7O13S

  • Molecular Weight

    1046.32

  • SMILES

    [H][C@]1(CCCN1C(=O)C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C(=O)[C@@H](NC(=O)[C@H](C(C)C)N(C)C(=O)CCCCCN1C(=O)CC(SC[C@H](N)C(O)=O)C1=O)C(C)C)[C@H](OC)[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(O)=O

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound