Cytochalasin A - CAS 14110-64-6

Cytochalasin A, a cell-permeable fungal toxin and oxidized derivative of cytochalasin B, is an inhibitor of HIV-1 protease (IC50 = 3 μM) . It inhibits actin polymerization, interferes with microtubule assembly by reacting with sulfhydryl groups, and serves as an antibiotic and bactericidal active agent.

Antifungal, HIV Protease

Proteases/Proteasome, Microbiology/Virology

14040

C29H35NO5

477.59

[H][C@]12[C@H](Cc3ccccc3)NC(=O)C11OC(=O)\C=C\C(=O)CCC[C@@H](C)C\C=C\C1[C@H](O)C(=C)[C@H]2C

-20°C

Ice Packs

Natural Product