Cytogenin - CAS 132971-59-6

Cytogenin, a coumarin derivative isolated from S. eurocidicum, exhibits multiple biological effects. It notably diminishes tumor mass in an Ehrlich murine spontaneous adenocarcinoma model with a daily administration of 25 mg/kg. Furthermore, cytogenin (30 and 100 mg/kg per day) counteracts the body weight reduction and the rise in plasma glucose levels induced by streptozotocin, along with reducing pancreatic macrophage infiltration in a diabetes mouse model. Additionally, at a dose of 100 mg/kg per day, it suppresses nitric oxide production triggered by zymosan and LPS, as well as the LPS-induced increase in Il-6 levels in isolated mouse macrophages.

Others, Interleukin, NO Synthase

Immunology/Inflammation, Others

132971-59-6

C11H10O5

222.19

O=C1OC(CO)=CC2=C1C(O)=CC(OC)=C2

-20°C

Ice Packs

Natural Product