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CZC-54252 hydrochloride - CAS 1784253-05-9

CZC-54252 hydrochloride - CAS 1784253-05-9

MF-0019528-01

$42.89 USD
$42.89 USD
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Product Details

  • Bioactivity

    CZC-54252 hydrochloride is a selective inhibitor of LRRK2 with IC50s of 1.85 nM and 1.28 nM for wild-type and G2019S LRRK2. CZC-54252 hydrochloride has a neuroprotective activity and attenuates G2019S LRRK2-induced human neuronal injury with an EC50 of 1 nM.

  • Target

    LRRK2

  • Related Pathways

    Autophagy

  • CAS Number

    1784253-05-9

  • Purity

    0.9928

  • Molecular Formula

    C22H26Cl2N6O4S

  • Molecular Weight

    541.45

  • SMILES

    Cl.COc1cc(ccc1Nc1ncc(Cl)c(Nc2ccccc2NS(C)(=O)=O)n1)N1CCOCC1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound