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Molfinity

D-65476 - CAS 249762-74-1

D-65476 - CAS 249762-74-1

MF-0117405-01

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Product Details

  • Bioactivity

    D-65476 is a type III receptor tyrosine kinase (Flt3) inhibitor. It inhibits the proliferation of TEL-Flt3 transfected BA/F3 cells in the absence of IL-3, with an IC50 of 0.2 μM, and is useful for researching Flt3-driven leukemia.

  • Target

    FLT

  • Related Pathways

    Tyrosine Kinase/Adaptors, Angiogenesis

  • CAS Number

    249687

  • Molecular Formula

    C21H18N2O3

  • Molecular Weight

    346.38

  • SMILES

    O=C(OC=1C=CC=2NC(=CC2C1)C(=O)C3=CC=4C=CC=CC4N3)CCC

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound