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D-69491 hydrochloride - CAS 346599-65-3
D-69491 hydrochloride - CAS 346599-65-3
SKU:MF-0110813-01
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Product Details
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Bioactivity
D-69491 hydrochloride is an inhibitor of HER-2 tyrosine kinase activity, blocking the phosphorylation of HER-2 and inhibiting the proliferation of SKOV-3 cells. It exhibits antitumor activity.
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Target
Interleukin, EGFR
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Related Pathways
Immunology/Inflammation, Tyrosine Kinase/Adaptors, JAK/STAT signaling, Angiogenesis
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CAS Number
346531
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Molecular Formula
C25H26Cl2FN7O3
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Molecular Weight
562.42
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SMILES
Cl.O=C1NC2=NC=NC(NC3=CC=C(F)C(Cl)=C3)=C2C1=CC=4NC(=CC4C)C(=O)NCCN5CCOCC5
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound