[D-Ala2]-GIP (human) - CAS 444073-04-5

Highly potent GIP receptor agonist (EC50 = 630 ± 119 pM) . Displays equivalent cAMP stimulating properties and improved resistance to enzymatic degradation compared to native GIP in cells expressing wild type GIP receptor. Improves glucose tolerance, insulin release and cognitive function in various animal models of obesity and diabetes. Displays neuroprotective effects in an MPTP model of PD.

IGF-1R

Tyrosine Kinase/Adaptors

444073-04-5

C226H338N60O66S

4983.58

-20°C

Ice Packs

Peptide