(d (CH2) 51, Tyr (Me) 2, Arg8) -Vasopressin - CAS 73168-24-8

Selective vasopressin V1A receptor antagonist. Inhibits vasopressin and oxytocin-induced increases in intracellular calcium concentrations in vitro (IC50 values are 5 and 30 nM respectively) . Exhibits potent and prolonged antivasopressor activity and induces anxiolytic-like effects in the dorsal, but not ventral, hippocampus in vivo.

Vasopressin Receptor

GPCR/G Protein

73136

C52H74N14O12S2

1151.38

O=C1CC2(SSC[C@@H](C(=O)N3[C@H](C(N[C@H](C(NCC(N)=O)=O)CCCNC(=N)N)=O)CCC3)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC4=CC=CC=C4)NC(=O)[C@H](CC5=CC=C(OC)C=C5)N1)CCCCC2

-20°C

Ice Packs

Peptide