D-G23 - CAS 1225141-73-0

D-G23 is a selective RAD52 inhibitor. It disrupts RAD52-mediated DNA repair pathways and suppresses the growth of cancer cells deficient in BRCA1 and BRCA2. D-G23 shows promise for research into homologous recombination-related cancers caused by BRCA1/2 mutations, such as hereditary breast and ovarian cancers.

DNA/RNA Synthesis

DNA Damage/DNA Repair, Cell Cycle/Checkpoint

1225068

C19H22N4O3

354.403

OCCCNC=1N=C(N=C2C=CC=CC21)NC3=CC(OC)=CC=C3OC

-20°C

Ice Packs

Small Compound