D-myo-Inositol-1,3,4,6-tetraphosphate (ammonium salt) - CAS 142507-74-2

The inositol phosphates (IPs) are a family of molecules produced by altering the phosphorylation status of each of the six carbons on the cyclic inositol structure. They act as second messengers, regulating a wide array of cellular functions. D-myo-inositol-1,3,4,6-tetraphosphate (Ins (1,3,4,6) -P4) largely acts an intermediate, serving as substrate for inositol-1,3,4,6-tetraphosphate 5-kinase to produce inositol-1,3,4,5,6-pentaphosphate, or inositol-1,3,4,6-tetraphosphate 2-kinase to give inositol-1,2,3,4,6-pentaphosphate. These inositol pentaphosphates can be further phosphorylated to produce inositol-1,2,3,4,5,6-hexakisphosphate, or phytic acid, which serves diverse roles in eukaryotic tissues. Ins (1,3,4,6) -P4 is a poor activator of the inositol 1,4,5-trisphospate receptor in vitro. Other functions of this IP remain to be elucidated.

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142431

C6H26N4O18P4

566.179

[NH2].[NH4+].[NH4+].[NH4+].O[C@H]1[C@@H](OP(O)([O-])=O)[C@H](OP(O)([O-])=O)[C@@H](O)[C@H](OP(O)([O-])=[O+])[C@H]1OP(O)([O-])=O

-20°C

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Small Compound