[D-Phe12, Leu14]-Bombesin - CAS 108437-88-3

Bombesin receptor antagonist that inhibits bombesin binding to rat brain with an IC50 value of 2 μM. Inhibits amylase release in vitro (IC50 = 4 μM) and attenuates bombesin-mediated suppression of food intake in vivo.

Bombesin Receptor

GPCR/G Protein

108346

C77H113F3N22O20

1724.9

C([C@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC(=O)[C@@H]1CCC(=O)N1)CCC(N)=O)=O)CCCNC(=N)N)=O)CC(C)C)=O)=O)CC(N)=O)=O)CCC(N)=O)=O)C(N[C@H](C(N[C@H](C(NCC(N[C@H](CC2=CC=CC=C2)C(N[C@H](C(N[C@@H](CC(C)C)C(N)=O)=O)CC(C)C)=O)=O)=O)[C@@H](C)C)=O)C)=O)C=3C=4C(NC3)=CC=CC4

-20°C

Ice Packs

Peptide