D-threo-PPMP hydrochloride - CAS 139889-65-9

D-threo-PPMP is a glucosylceramide (GlyCer) synthetase inhibitor.1,2It is the active enanantiomer and enzymatic inhibitory component of the racemic DL-threo-PPMP . In MDCK kidney epithelial cells, D-threo-PPMP induces a 70% reduction in cell growthin vitroat 20 μM and significantly inhibits DNA synthesis at 3 μM.3

Transferase, Others

Others, Metabolism

139815

C29H51ClN2O3

511.19

Cl.CCCCCCCCCCCCCCCC(=O)N[C@H](CN1CCOCC1)[C@H](O)c1ccccc1

-20°C

Ice Packs

Small Compound