[D-Trp34]-Neuropeptide Y - CAS 153549-84-9

Potent neuropeptide Y (NPY) Y5 receptor agonist (pEC50 values are 7.82, 6.28, 6.44 and > 6 at rat Y5, Y4, Y1 and Y2 receptors respectively) that displays > 26-fold, > 1000-fold and > 1000-fold selectivity over Y1, Y2 and Y4 receptors respectively. Induces hyperphagia, body weight gain, adiposity, hypercholesterolemia, hyperinsulinemia and hyperleptinemia in vivo. Orally active.

Neuropeptide Y Receptor

Neuroscience, GPCR/G Protein

153456

C196H289N55O56

4311.77

-20°C

Ice Packs

Peptide