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Molfinity

D34-919 - CAS 1011641-78-3

D34-919 - CAS 1011641-78-3

MF-0142900-01

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Product Details

  • Bioactivity

    D34-919 is a potent inhibitor of the ALDH1A3-PKM2 interaction, effectively inhibiting the ALDH1A3-mediated tetramerization enhancement of PKM2. Treatment mediated by D34-919 both in vitro and in vivo enhances and restores apoptosis and sensitivity in glioblastoma (GBM) cells induced by radiochemotherapy.

  • Target

    Dehydrogenase, PKM

  • Related Pathways

    Metabolism

  • CAS Number

    1011560

  • Molecular Formula

    C22H27N5OS

  • Molecular Weight

    409.55

  • SMILES

    N#CC=1C(=NC(=NC1N2CCC(C(=O)N)CC2)SC)C=3C=CC(=CC3)C(C)(C)C

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound