DA-1241 - CAS 1914136-10-9

DA-1241 is a GPR119 agonist. By activating GPR119, it downregulates NFκB signaling, thereby inhibiting macrophage differentiation. Whether used alone or in combination with DPP4 inhibitors, DA-1241 can alleviate liver inflammation and restore the expression of liver genes linked to inflammation. It is applicable in the research of metabolic dysfunction-associated steatohepatitis (MASH) .

GPCR

GPCR/G Protein, Endocrinology/Hormones

1914117

C25H31F2N5O2

471.543

FC1=CC(OCCCC2CCN(C3=NC=C(C=N3)CC)CC2)=CC(F)=C1C4=NOC(=N4)C(C)C

-20°C

Ice Packs

Small Compound