DA-6886 - CAS 1645260-76-9

DA-6886 is an agonist 5-Hydroxytryptamine receptor 4 (5-HT4) . DA-6886 induced relaxation of the rat oesophagus preparation in a 5-HT4 receptor antagonist-sensitive manner. The evaluation of DA-6886 in CHO cells expressing hERG channels revealed that it inhibited hERG channel current with an pIC50 value of 4.3, indicating that the compound was 1000-fold more selective for the 5-HT4 receptor over hERG channels.

5-HT Receptor

GPCR/G Protein, Neuroscience

1645175

0.9999

C19H28Cl2N6O2

443.37

Cl.O=C(NCC1CCN(CCCN2N=NC=C2)CC1)C3=CC(Cl)=C(N)C=C3OC

-20°C

Ice Packs

Small Compound