DA-PROTAC - CAS 2488660-12-2

DA-PROTAC is a potent degrader of the copper ion-transport proteins Atox1 and CCS, capable of binding to both proteins and facilitating their association with E3 ligase. This interaction enhances the ubiquitination and subsequent proteasomal degradation of Atox1 and CCS. DA-PROTAC is utilized in triple negative breast cancer research [1].

PROTACs, Ligand for E3 Ligase

PROTAC

2488660-12-2

C46H50BrF2N7O8S2

1010.96

N(C(COCCCOCC(NC(C(=O)N1[C@H](C(NCC2=CC=C(C=C2)C3=C(C)N=CS3)=O)C[C@@H](O)C1)C(C)(C)C)=O)=O)C=4C5=C(SC4C(NC6=C(Br)C=C(F)C=C6F)=O)N=C7C(=C5)CCC7

-20°C

Ice Packs

PROTAC