DA ZP1 - CAS 1816254-69-9

DA ZP1 (diacetylated Zinpyr1), a highly sensitive fluorogenic Zn (II) sensor (KdZn2+= 0.6 nM), efficiently images and isolates pancreatic β-cells and β-like cells in vitro and purifies live stem cell-derived β-like cells. It also enables imaging of transplanted islet grafts and endogenous mouse islets in vivo. DA ZP1 is initially non-fluorescent; however, its interaction with Zn (II) ions triggers hydrolytic cleavage of the acetyl groups, creating a robust fluorescent signal with excitation and emission maxima (λ) at 490 nm and 522 nm, respectively.

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1816254-69-9

C50H40Cl2N6O7

907.81

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