Molfinity

Dabrafenib - CAS 1195765-45-7

SKU:MF-0016459-01

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Size 5 mg 1 mL - 10 mM (in DMSO) 10 mg 25 mg 50 mg 100 mg 200 mg

Product Details

Bioactivity
Dabrafenib (GSK2118436A) is a Raf inhibitor that inhibits C-Raf and B-RafV600E (IC50=5/0.6 nM) and is ATP-competitive. Dabrafenib exhibits antitumor activity for the treatment of B-RafV600E-mutated melanoma.
Target
Raf
Related Pathways
MAPK
CAS Number
1195713
Purity
>99.99%
Molecular Formula
C23H20F3N5O2S2
Molecular Weight
519.56
SMILES
CC(C)(C)c1nc(c(s1)-c1ccnc(N)n1)-c1cccc(NS(=O)(=O)c2c(F)cccc2F)c1F
Storage Temperature
-20°C
Shipping Conditions
Ice Packs
Category
Small Compound