Dactolisib Tosylate - CAS 1028385-32-1

Dactolisib Tosylate (BEZ235 Tosylate) is a dual kinase inhibitor targeting PI3K and mTOR, with IC50 values of 4, 75, 7, and 5 nM for PI3Kα, β, γ, and δ, respectively. It also inhibits mTORC1 and mTORC2.

MTOR, Autophagy, PI3K

Autophagy, PI3K/Akt/mTOR signaling

1028352

0.9991

C37H31N5O4S

641.74

Cc1ccc(cc1)S(O)(=O)=O.Cn1c2cnc3ccc(cc3c2n(-c2ccc(cc2)C(C)(C)C#N)c1=O)-c1cnc2ccccc2c1

-20°C

Ice Packs

Small Compound