Dalvotoclax - CAS 2416927-21-2

Dalvotoclax (Example 8) is a selective inhibitor of BCL-2 that exhibits good liver microsomal stability. It effectively suppresses the activity of the anti-apoptotic proteins BCL-2 and BCL-XL and is applicable for research on B-cell leukemia.

Bcl-2 Family

Apoptosis

2416904

C45H47ClF3N7O8S

938.41

C(C1=C(CC(C)(C)CC1)C2=C(Cl)C=C(C(F)(F)F)C=C2)N3CCN(CC3)C4=CC(OC=5C=C6C(=NC5)NC=C6)=C(C(NS(=O)(=O)C7=CC(N(=O)=O)=C(NC[C@H]8COCCO8)C=C7)=O)C=C4

-20°C

Ice Packs

Small Compound