Damulin A - CAS 1202868-74-3

Damulin A is an active dammarane-type saponin isolated from Gynostemma pentaphyllum and belongs to a group of structurally related compounds whose anticancer structure–activity relationships have been deeply explored. Comparative investigations reveal that double bonds positioned at C20 (21) and C20 (22) and hydroxyl modification at C-2 significantly contribute to cytotoxicity, as evidenced by proliferation inhibition in A549 cells. These findings confirm the importance of Damulin A within the broader context of Gynostemma-derived anticancer leads.

Others

Others

1202791

0.9833

C42H70O13

783.01

C[C@]12[C@@]([C@]3(C)[C@@](CC1)(C(C)(C)[C@@H](O[C@H]4[C@H](O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)[C@@H](O)[C@H](O)[C@@H](CO)O4)[C@H](O)C3)[H])(C[C@@H](O)[C@]6([C@@]2(C)CC[C@@H]6\C(=C\CC=C(C)C)\C)[H])[H]

-20°C

Ice Packs

Natural Product