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Molfinity

Danicopan - CAS 1903768-17-1

Danicopan - CAS 1903768-17-1

MF-0012208-01

$103.81 USD
$63.05 USD $103.81 USD
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Product Details

  • Bioactivity

    Danicopan (ACH-4471) (ACH-4471) is a selective, orally active small molecule factor D inhibitor with high binding affinity to human factor D, with a Kd value of 0.54 nM. Danicopan (ACH-4471) inhibits the activity of the complement replacement pathway (APC) and may block the complement replacement pathway in paroxysmal nocturnal hemoglobinuria (PNH) and atypical hemolytic uremic syndrome (aHUS) .

  • Target

    Complement System

  • Related Pathways

    Immunology/Inflammation

  • CAS Number

    1903768-17-1

  • Purity

    0.9994

  • Molecular Formula

    C26H23BrFN7O3

  • Molecular Weight

    580.41

  • SMILES

    CC(=O)c1nn(CC(=O)N2C[C@H](F)C[C@H]2C(=O)Nc2cccc(Br)n2)c2ccc(cc12)-c1cnc(C)nc1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound