Danshensu sodium - CAS 81075-52-7

Danshensu sodium (Dan shen suan A) is a phenolic compound with oral bioactivity that activates Nrf2/HO-1 and inhibits the NF-κB pathway. It reduces reactive oxygen species (ROS) production, enhances antioxidant defenses, and suppresses intrinsic apoptotic pathways. Additionally, Danshensu sodium exhibits significant antiviral activity against SARS-CoV-2 with an EC50 of 0.97 μM. It offers antioxidant, anti-apoptotic, and anti-inflammatory benefits for the lungs, presenting potential for research in COVID-19, cardiovascular, and cerebrovascular diseases.

Nrf2, Apoptosis, Reactive Oxygen Species, NF-κB, SARS-CoV

NF-κB, Immunology/Inflammation, Microbiology/Virology, Metabolism, Apoptosis

81075-52-7

C9H9NaO5

220.16

[O-]C([C@H](O)CC1=CC(O)=C(C=C1)O)=O.[Na+]

-20°C

Ice Packs

Natural Product