Dantrolene sodium hemiheptahydrate - CAS 24868-20-0

Dantrolene depresses excitation-contraction coupling in skeletal muscle by binding to the ryanodine receptor 1 and decreasing intracellular calcium concentration. Ryanodine receptors mediate the release of calcium from the sarcoplasmic reticulum, an essential step in muscle contraction. Dantrolene sodium hemiheptahydrate (Sodium dantrolene) is the sodium salt form of dantrolene, a hydantoin derivative, and direct-acting skeletal muscle relaxant.

ROS, Autophagy, Apoptosis, Calcium Channel

Autophagy, Membrane transporter/Ion channel, Apoptosis, Metabolism, Immunology/Inflammation

24848

0.9972

C14H9N4NaO5·3.5H2O

399.29

O.O.O.O.O.O.O.[NaH].[NaH].[O-][N+](=O)c1ccc(cc1)-c1ccc(C=NN2CC(=O)NC2=O)o1.[O-][N+](=O)c1ccc(cc1)-c1ccc(C=NN2CC(=O)NC2=O)o1

-20°C

Ice Packs

Small Compound